HIV induces expression of complement component C3 in astrocytes by...
AbstractBackgroundAbnormal activation of the complement system contributes to some central nervous system diseases but the role of complement in HIV-associated neurocognitive disorder (HAND) is...
View ArticleMDA-9/Syntenin/SDCBP: new insights into a unique multifunctional scaffold...
AbstractTumor metastasis comprises a series of coordinated events that culminate in dissemination of cancer cells to distant sites within the body representing the greatest challenge impeding effective...
View ArticleTumor-specific imaging through progression elevated gene-3 promoter-driven...
Bhang and colleagues have developed a tumor-specific imaging strategy that uses the progression elevated gene-3 (PEG-3) promoter, known to be specifically associated with malignant transformation, to...
View ArticleNovel ZnO hollow-nanocarriers containing paclitaxel targeting...
AbstractLow pH in the tumor micromilieu is a recognized pathological feature of cancer. This attribute of cancerous cells has been targeted herein for the controlled release of chemotherapeutics at the...
View ArticleUpregulation of neuronal astrocyte elevated gene-1 protects nigral...
AbstractThe role of astrocyte elevated gene-1 (AEG-1) in nigral dopaminergic (DA) neurons has not been studied. Here we report that the expression of AEG-1 was significantly lower in DA neurons in the...
View ArticleMulti-nucleated cells use ROS to induce breast cancer chemo-resistance in...
AbstractAlthough there is a strong correlation between multinucleated cells (MNCs) and cancer chemo-resistance in variety of cancers, our understanding of how multinucleated cells modulate the tumor...
View ArticleRegulation of neuroblastoma migration, invasion, and in vivo metastasis by...
AbstractDespite multi-modality treatments, prognosis for advanced stage neuroblastoma (NB) remains challenging with residual long-term disabilities in survivors. Advanced stage NB is metastatic, which...
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